An age-equivalent summary
Biological age summarizes a health profile on an age-like scale. It does not measure the age of every cell, predict your lifespan or establish that aging has been reversed. A result can change because the measurements, their conditions or the information available have changed. Think of it as a question to understand in context, rather than a verdict about your body.
Two methods, two different meanings
The laboratory Phenotypic Age model combines chronological age with nine blood measurements. It is distinct from DNAm PhenoAge, a DNA methylation model. Connefi’s source implements the original laboratory coefficients distributed in the BioAge research software. Its separate wearable wellness method uses other health signals and has not been clinically validated as PhenoAge. Those outputs should not be blended or compared as though they were the same test.
The evidence behind a laboratory estimate
The nine measurements are albumin, creatinine, glucose, C-reactive protein, lymphocyte percentage, mean corpuscular volume, red cell distribution width, alkaline phosphatase and white blood cell count. Connefi’s implementation requires a complete confirmed panel, consistent units and age at specimen collection. Missing results are not filled with averages or AI-generated values. CRP and hs-CRP represent a single input. Laboratory workflow availability remains dependent on the released app.
Compare like with like
A specimen date tells you when evidence was collected; opening the app does not make an older panel new. Method versions, sources and recording conditions matter when interpreting a trend. Coverage describes the data available, not the probability that the estimate is correct. A continuation of a recorded trend is a projection, not a prediction of a treatment effect.
Keep the purpose in view
These are wellness explanations, not diagnostic instructions. Research in population cohorts does not establish equal accuracy for every person or condition. Bring questions about laboratory results to a qualified healthcare professional. Use Methods & Limitations to understand the distinction between inputs, modeled estimates and the context shown alongside them.
Research & sources
Research provides context; it does not validate Connefi’s exact scores or establish individual outcomes.